One interesting thing I've noticed is that the 4800 has a limited sense of humor when it comes to paper size, compared to the 2100. I've been cutting some odd sizes to save paper which you can feed into the 2100 without any problem - it doesn't care if what you feed in is different to what you tell it in the driver. With the 4800 the paper needs to match the size you've specified in the driver.

Regarding loading, I've used the front tray, rear manual feed slot and rollpaper and haven't had any problems to date.

This is the first printer I've owned with a large front tray, where you load the paper face down and it gets fed in and around, and returns on top of the tray. Don't know if I'll ever make use of all that storage capacity but the front tray happens to fit in well with the workspace I have available in so I've ended up using the tray for holding my primary cut sheet stock.

The rear manual feed slot, located infront of the rollpaper, has also worked well enough. A little clumsy perhaps - the addition of a small sliding plastic guide for the left side of paper would've been handy. You do have to slide the paper in fairly firmly before the printer is satisfied it is loaded ok. It's almost as if Epson have made this method of feeding paper available but don't expect many people to use it. I'll probably only use it to feed in papers I don't use that often.

The rollpaper setup has worked well. Even though rollpaper isn't my favorite thing(!), I may end up going this route based on the availability of 17" cut vs rollpaper.